| Head of State | President | Macky Sall |
| Head of Government | Prime Minister | Amadou Ba |
| Finance | Minister of Finance and Budget | Amadou Moustapha Bâ |
| Foreign | Minister of Foreign Affairs and Senegalese Diaspora | Aïssata Tall Sall |
| Defense | Minister of the Armed Forces | Sidiki Kaba |
| Health | Minister of Health and Social Action | Marie Khémesse Ngom Ndiaye |
| Justice | Keeper of the Seals, Minister of Justice | Ismaïla Madio Fall |
| Agriculture | Minister of Agriculture and Food Security | Aly Ngouille Ndiaye |
| Minister of Fisheries and Maritime Economy | Papa Sagna Mbaye |
| Minister of Livestock Breeding and Animal Production | Aly Saleh Diop |
| Energy | Minister of Oil and Energy | Sophie Gladyma |
| Natural Resources | Minister of Mines and Geology | Oumar Sarr |
| Minister of Water and Sanitation | Serigne Mbaye Thiam |
| Education | Minister of National Education | Cheikh Omar Anne |
| Minister of Higher Education, Research and Innovation | Moussa Baldé |
| Economy | Minister of Industrial Development and Small and Medium Industries | Moustapha Diop |
| Minister of Microfinance and Solidarity-Based Economy | Victorine Ndeye |
| Minister of Economy, Planning and Cooperation | Oulimata Sarr |
| Minister of Commerce and Consumption, Government Spokesperson | Abdou Karim Fofana |
| Digital/IT | Minister of Communications, Telecommunications and Digital Economy | Moussa Bokar Thiam |
| Interior | Minister of the Interior | Antoine Félix Abdoulaye Diome |
| Environment | Minister of the Environment and Ecological Transition | Alioune Ndoye |
| Labor | Minister of Professional Education and Integration | Mariama Sarr |
| Minister of Labor, Social Dialogue and Institutional Relations | Samba Sy |
| Others | Minister of Civil Service and Public Service Renewal | Gallo Bâ |
| Minister of Transport, Land-Based Infrastructures and Connectivity | Amadou Mansour Faye |
| Minister of Women, Family and Child Protection | Fatou Diané |
| Minister of Tourism and Leisure | Mame Mbaye Ka Niang |
| Minister of Territorial Governance and Land Management | Mamadou Talla |
| Minister of Sports | Yankhoba Diattara |
| Minister of Urban Development, Housing and Public Hygiene | Abdoulaye Seydou Sow |
| Minister of Culture and Heritage | Alioune Sow |
| Minister of Youth, Entrepreneurship and Labor | Pape Malick Ndour |
| Minister of Community Development, Social and Territorial Equity | Samba Ndiobène Ka |
| Minister of Arts and Crafts and Transformation of the Informal Sector | Pape Amadou Ndiaye |
| Minister of Air Transport and Airport Infrastructure | Doudou Kâ |
| Minister to the Minister of Foreign Affairs in charge of the Diaspora | Annette Seck |
| Minister to the Minister of Justice in charge of Good Governance and Human Rights | Mamadou Saliou Sow |
| Minister to the Minister of the Interior in charge of Civil Protection | Birame Faye |
| Minister to the Minister of Water in charge of Flood Prevention | Yankhoba Issa Diop |
