| Head of State | President | Félix Antoine Tshisekedi |
| Head of Government | Prime Minister | Jean Michel Sama Lukonde Kyenge |
| Finance | Minister of Finance | Nicolas Kadima Kazadi |
| Foreign | Minister of Foreign Affairs | Christophe Lutundula Apala Pen'apala |
| Defense | Minister of Defense and Veterans Affairs | Gilbert Kabanda Rukemba |
| Health | Minister of Public Health, Hygiene And Prevention | Jean-Jacques Bungani Mbanda |
| Justice | Minister of State, Minister of Justice and Keeper of the Seals | Rose Mutombo Kiese |
| Agriculture | Minister of Agriculture | Désire Nzinga Bilihanzi |
| Minister of Fisheries and Livestock | Adrien Bokele Djema |
| Energy | Minister of Water Resources and Electricity | Olivier Mwenze Mukaleng |
| Natural Resources | Minister of Hydrocarbons | Didier Budimbu Ntubuanga |
| Minister of Mines | Antoinette Nsamba Kalambayi |
| Education | Minister of Primary, Secondary And Technical Education (EPST) | Tony Mwaba Kazadi |
| Minister of Higher and University Education | Muhindo Nzangi |
| Minister of Vocational Trainings and Trades | Antoinette Kipulu Kabenga |
| Economy | Minister of National Economy | Jean-Marie Kalumba Yuma |
| Minister of Industry | Julien Paluku Kahongya |
| Minister of State, Minister of Entrepreneurship and Small and Medium Enterprises | Eustache Muhanzi |
| Minister of Foreign Trade | Jean-Lucien Bussa Tongba |
| Minister of Rural Development | Francois Rubota Masumbuko |
| Digital/IT | Minister of Posts, Telecommunications, and New Information and Communication Technologies (PTNTIC) | Augustin Kibassa Maliba Lubalala |
| Minister of Digital | Désiré Cashmir Eberande Kolongele |
| Interior | Minister of the Interior, Security, Decentralization and Customary Affairs | Daniel Asselo Okito Wankoy |
| Media | Minister of Communications And Media | Patrick Muyaya Katembwe |
| Environment | Minister of The Environment And Sustainable Development | Eve Bazaiba Masudi |
| Labor | Minister of Employment, Labor and Social Welfare | Ms. Ndusi Ntembe |
| Others | Minister of Regional Integration | Didier Mazenga Mukanzu |
| Minister of Human Rights | Albert Fabrice Puela |
| Minister of State, Minister of the Budget | Aimé Boji |
| Minister of Transport, Communication Routes and Opening Up | Cherubin Okende Senga |
| Minister of State, Minister of Town Planning and Housing | Pius Muabilu Mbayu Mukala |
| Minister of State, Minister of Regional Planning | Guy Loando Mboyo |
| Minister of State, Minister of Planning | Christian Mwando Nsimba |
| Minister of Social Affairs, Humanitarian Actions and National Solidarity | Modest Mutinga Mutushayi |
| Minister of State, Minister of Infrastructure and Public Works | Alexis Gizaro Muvuni |
| Minister of Scientific Research and Technological Innovation | José Mpanda Kabangu |
| Minister of Culture, Arts and Heritage | Catherine Katumbu Furaha |
| Minister of the Civil Service, Modernization of Administration and Innovation of the Public Service | Jean-Pierre Lihau Ebua |
| Minister of Gender, Family and Children | Gisele Ndaya Luseba |
| Minister of Sports and Recreation | Serge Tshembo Nkonde |
| Minister of Youth, Initiation to New Citizenship and National Cohesion | Yves Zola Bunkulu |
| Minister of Relations with Parliament | Anne-Marie Karume Bakaneme |
| Minister of State, Minister of Portfolio | Adele Kahinda Mayina |
| Minister of Land Affairs | Aimé Sakombi Molendo |
| Minister of Tourism | Modero Nsimba Matondo |
| Minister to the President | Nana Manwanina Kiumba |
