| Head of State | President | Paul Biya |
| Head of Government | Prime Ministre | Joseph Dion Ngute |
| Finance | Minister of Finance | Paul Louis Motazse |
| Foreign | Minister of External Relations | Lejeune Mbella Mbella |
| Health | Minister of Public Health | Malachie Manaouda |
| Defense | Minister Delegate at the Presidency in Charge of Defence | Joseph Beti Assomo |
| Justice | Minister of State, Minister of Justice and Keeper of Seals | Laurent Esso |
| Agriculture | Minister of Agriculture and Rural Development | Gabriel Mbairobe |
| Minister of Livestock Fisheries and Animal Industries | Taiga |
| Energy | Minister of Energy and Water Ressources | Gaston Eloundou Essomba |
| Natural Resources | Minister of Industry, Mines and Technological Development | Gabriel Dodo Ndoke |
| Education | Minister of Secondary Eduaction | Pauline Nalova Lyonga Egbe |
| Minister of Basic Education | Laurent Serge Etoundi Ngoa |
| Economy | Minister of Commerce | Luc Magloire Mbarga Atangana |
| Minister of Economy, Planning and Regional Development | Alamine Ousmane Mey |
| Minister of Small and Medium- sized Enterprises Social Economy and Handicrafts | Achille Bassilekin III |
| Digital/IT | Minister of Posts and Telecommunications | Minette Libom Lii Likeng nee Mendomo |
| Minister of Scientific Research and Innovation | Madeleine Tchuinte |
| Interior | n/a | n/a |
| Media | Minister of Communication | René Emmanuel Sadi |
| Environment | Minister of the Environment, Protection of Nature and Sustainable Development | Pierre Helé |
| Minister of Forestry and Wildlife | Jules Doret Ndongo |
| Labor | Minister of Employment and Vocational Training | Bakary Issa Tchiroma |
| Minister of Labor and Social Security | Gregroire Owona |
| Others | Minister of Public Service and Administrative Reforms | Joseph Le |
| Minister of Arts and Culture | Pierre Ismaël Bidoug Kpwatt |
| Minister of Territorial Administration | Paul Atanga Nji |
| Minister of Social Affairs | Pauline Irène Kendeck, née Nguene |
| Minister of Decentralization and Local Development | Georges Elanga Obam |
| Minister of State Property and Land Tenure | Henri Eyebe Ayissi |
| Minister of Housing and Urban Development | Célestine Ketcha Courtès |
| Minister of Youth Affairs and Civic Education | Mounouna Foutsou |
| Minister of Women Empowerment and Family | Marie-Thérèse Abena Ondoa, née Obama |
| Minister of Sport and Physical Education | Narcisse Mouelle Kombe |
| Ministry of Transport | Jean Ernest Masséna Ngalle Bibehe |
| Ministry of Public Works | Emmanuel Nganou Djoumessi |
| Minister of State, Minister Tourism and Leisure | Bello Bouba Maigari |
| Minister of State, Minister of Higher Education | Jacques Fame Ndongo |
| General Secretary | Ferdinand Ngoh Ngoh |
